M2 Pk Tumor Marker. for early detection of colorectal cancers The M2PK Test is a noninvasive screening method for the early detection of colorectal cancers and polyps which are known to be the precursors of colorectal cancer The M2PK Test which is used for stool analysis is available either as fully quantitative ELISA Test or as a rapid test that can be performed by any general practitioner.

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Expression of the dimeric M2 isoenzyme of pyruvate kinase termed Tumor M2PK is increased in some human cancers This study evaluates the potential role of preoperative Tumor M2PK as a marker of prognosis in patients with pancreatic malignancy Methods.

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The median (interquartile range) tumour M2PK concentration for the CRC patients was 86 U ml −1 (28–180) with a striking difference between colon and rectum cancer (95 U ml −1 62–184 and 55.

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Tumor M2PK is a synonym for the dimeric form of the pyruvate kinase isoenzyme type M2 (PKM2) a key enzyme within tumor metabolism Tumor M2PK can be elevated in many tumor types rather than being an organspecific tumor marker such as PSA.

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Proliferating cells in particular tumor cells express a dimeric isoenzyme of pyruvate kinase termed Tumor M2 pyruvate kinase In the last.

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The metabolic marker type M2 tumour pyruvate kinase

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TU M2PK Tumor … [The Significance of Marker for Lung

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Therefore Tumor M2PK is an organunspecific biomarker which reflects the metabolic activity and proliferation capacity of tumors Tumor M2PK in stool is a marker for early detection of colorectal cancer and polyps (Kumar et al 2007 Tonus et al 2006).